From Lai Rong's genetic pig of Harvard It is expected to be offered and transplant the organ

From Lai Rong's genetic pig of Harvard It is expected to be offered and transplant the organ
In the classical science fiction " wish of checking the jasmine " that the science fiction writer cloth Ryan created of Britain, because of suffering from first worry, check jasmines can't play freely like ordinary child, her parents have grown a piglet for her, this pig is planted into and checks the gene of the jasmine, have a human heart, this heart will be transplanted to checking in the body of jasmine finally, save her life
Perhaps in the near future, the plot in the science fiction will become reality. Yesterday, provincial hospital cooperate with Harvard University and introduce, enter signing ceremony of field, scientific research of China, hold by four the intersection of genetic engineering and pig for the first time. Perhaps will come for some day, these pigs that was changed over to the human gene can offer organs such as liver, kidney suitable for transplanting,etc. to mankind, and the skin, blood vessel even bone of the genetic pig may become a part of the human body.
Origin is unusual
Four genetic pigs come from Harvard Medical School
33 -year-old big to suffer from uremia Cheng Yang, extend life, most loud hope to go on renal transplantation, but he and several relative's mixing types are all unsuccessful. Now, Yang ChengWei can only dialyse and maintain the life by the blood.
In provincial hospital, have some as him because depleted waiting patienting to make organ transfer operation organ. In the afternoon of yesterday, when Yang waits for another relative's mixing result at home anxiously as big and wife, one is enough to shake China organ transplant circle, bring the signing ceremony of the dawn to hold in province the People's Hospital for the depleted patient of numerous organs. David H.Sachs, the doctor of medicine, department's professor outside the medical college of Harvard University, he succeeds in cultivating a kind of special genetic engineering pig, if the human patient transplants organs such as the liver or kidney of this kind of pig,etc., will produce obviously repel the phenomenon. The afternoon of yesterday, the signing ceremony that Dr. David H.Sachs cooperated with the People's Hospital of Sichuan Province on behalf of Harvard Medical School, the provincial hospital will introduce four genetic pigs (two hectograms of mothers) for the first time Enter China's scientific research field. The laboratory where province the People's Hospital will specialize in the genetic pig names " David H.Sachs different kind of organ transplant laboratories " as ,It is the permanent visiting professor to still engage Dr. David H.Sachs at the same time.
According to provincial hospital Vice President Deng ShaoPing, the genetic engineering pig changes people's gene over to the organizing in cells all over of the pig promptly, and it causes the different kind of antigen repelled to reject surface of pig's cell by way of genetic engineering, let the human body easier to accept. It is reported four genetic pig that provincial hospital introduce this time, breed 20 over the intersection of generation and purebred pig the intersection of U.S.A. and different kinds of the intersection of organ transplant and laboratory, pig offspring changing over to the human gene.
The use is unusual
Its organ Save the human life
Yesterday, when being double-current and field, the intersection of province and in the institute of lab animals the People's Hospital, the monkey in the iron cage shouts loudly. In the near future, one genetic pig which these monkeys will breed with provincial hospital, from " David H.Sachs different kind of organ transplant laboratories " Test before medical researchers carry on clinically.
Transplant to Dr. Yang HongJi, director of centre, and claim according to the provincial hospital, the pig is and similar to people in the weight physiologically, its organ and the people's organ are similar in size, it is relatively fast and simple to perform a surgical operation; Secondly because the pig is not a primate, will not initiate more disputes as chimpanzee and baboon.
After introducing the genetic pig, the provincial hospital tests before launching soon clinically, includes the pork liver to pour into and test (namely connected the genetic pig's pork liver to monkey's body outside the body of the monkey, carry on the liver function test) ,This test will canvass a kind of new complementary treatment means for the depleted patient of acute liver, before transplantation technology has not been ripe, the genetic pig's pork liver can be regarded as " liver of transition " of the critical patient ,Plant outside the human body in order to save the life, wait for the appropriate liver source to gain time. In addition medical personnel carry on genetic the intersection of pig and insulin to reach monkey transplant and test also, this test may bring more appropriate treatment means to the diabetic.
Vice President Deng ShaoPing says, the medical personnel in the laboratory will strive to make the great breakthrough within 3~5 years, let the genetic pig which the institute of lab animals of provincial hospital feeds can offer liver, kidney,etc. to mankind and can be used as the organ that is transplanted, and carry on the different kind of organ transfer operations. In addition, the provincial hospital will also cooperate with other research units, will further develop various biomaterials which will utilize the genetic pig, for example the skin of the genetic pig can play a role in protecting to the patient burning it, the ordinary pigskin transplanted in order to burn patients now may present the rejection; The genetic pig's blood vessel can substitute the artificial blood vessel after decorating, even pig's bone can also " enrich the bone " for the flawed or damaged patient of bone after dealing with .
The treatment is unusual
" luxurious house " It is aseptic to require The feed must be special
Continue flat the intersection of Vice President and introduction according to Deng, because of four the intersection of genetic engineering and pig that introduce this time through quarantining, examine and many kinds of complicated links, it is estimated that settles down during 3 to 6 months in the institute of lab animals of the People's Hospital of the province formally. At present, the base of Jianyang of institute of lab animals of provincial hospital has already launched preparatory work, plan to make for four genetic pigs " The luxurious house " .
David H.Sachs claim for can " similar to " with the human body ,The weight of the genetic pig is limited to 100 kilograms, the body is long about 1 point 5 meters. After four genetic pigs settle down in Chengdu formally, Harvard Medical School will send expert's group, offer technological guidance for raising these Hi-Tech pigs. Though the size is similar to ordinary pig, the genetic pig will enjoy the high-level treatment. Transplant introduction of Dr. Yang HongJi, director of centre according to the provincial hospital, four genetic pigs will grow in the aseptic environment, the room is clean and neat, the temperature of feeding the house will be controlled within the range of suring too. In addition, the feed which feeds the genetic pig adds the special feed that various science made after filling a prescription on the basis of ordinary pig feed.
It is reported, after four genetic pigs settle in the provincial hospital, the reproduction that the institute of lab animals of the People's Hospital of the province will be mainly responsible for the genetic pig is raised, and David H.Sachs different kind of organ transplant laboratories will carry on the test for scientific research. If these experiments can be used in clinic finally, will wait for the patient of organ transplant to bring good news. After Dr. Yang HongJi claims, different kind of organ transplantation technology is ripe that and reaches certain scale, the operation expenses will be far lower than the present transfer operation expenses. Show according to the statistical data which Ministry of Public Health publish on the " lancet " magazine of October of 2008, only in China, 1,500,000 organ depleted patients wait to do the operation of organ transplant every year.
Chengdu Business reporter Lee's weather whistle
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