The gene of persons who blush is defective to drink Or increase and suffer from cancer of the esophagus dangerously

The gene of persons who blush is defective to drink Or increase and suffer from cancer of the esophagus dangerously
Have a get-together and increase at the end of the year, it is a lot that wine cups and mora chips lying about in disorder, it is apt to blush to drink, someone is regarded as the behavior of the easy supersession of alcohol, but it is actually on the contrary that scientific research shows. After a lot of people drink, the skin on the face, on one's body will turn red, because often happen on Asians' body, known as " Asian Flush " , " Asian Red " Or " Asian Glow " . A lot of people think this is the response allergic to alcohol, it doesn't matter, continue drinking ignoring, or attempt to relieve by taking antiallergic. It is a fact that acetic aldehyde that the alcohol supersession produces piles up in the body to in fact drink and blush easily, with having while being allergic no relation.
Scientific research prove, have, drink person of response blushed because their participate in supersession gene of the enzyme of alcohol defective, therefore cause poisonous acetic aldehyde to accumulate in the body in a large amount, cause the blood vessel to expand, cause and blush the response. More important, this genetic defect will also increase the danger of suffering from cancer of the esophagus.
Let us see what a supersession alcohol is at first. After drinking, alcohol is absorbed in the digestive tract, entered blood, except less than 10% of the quantity is to discharge by lung and kidney with the ethanol true features, the main supersession takes place in the liver. To put it briefly, alcohol passes the ethanol dehydrogenase (ADH) at first Catalyze, the supersession gets acetic aldehyde. Acetic aldehyde will step forward in second aldehyde dehydrogenase 2(ALDH2) Function under turn into second sour,second is sour participate in a plurality of internal supersession routes, get the carbon dioxide and water finally, discharge outside the body.
The danger of drinking and bringing mainly comes from acetic aldehyde, it is the arch-criminal making you blush too. Acetic aldehyde is all toxicant to a lot of tissues and organs, may cause DNA to damage, is thought to have many kinds of carcinogenic effects, even do the luring and turning in animal's test into pharmaceutical of cancer model with acetic aldehyde.
ALDH2 of acetic aldehyde of full-time supersession seems particularly important. If has gone wrong, acetic aldehyde is easy to pile up in a large amount, you will blush quickly. Why some people ALDH2 those have strong ability, do some people have weak ability?
The question lies in the gene of the code ALDH2 albumen, if this gene has the defect, will get and have no activity, or albumen with very little activity, it is unable to decompose acetic aldehyde. The longer time acetic aldehyde is held up in the body, the greater the damage to the organism is. And because the question lies in the gene, basically this is grown it is powerless. Studies have suggested, such genetic defect is in East Asia the philtrum is more common, there are about 36% of the native in East Asia (Japan, China and South Korean)s Phenomenon that will drink and blush.
Once scientists carried on research to the crowd of Japan and Taiwan, the result showed to person getting drunk, gene this may take place have important influence while being high by cancer of the esophagus to blush at the same time. The scientists point out a doctor, can be through inquiring it is very apt to blush to judge whether they have ALDH2 defects whether the patient drinks, this kind of patient may be higher to suffer from the probability of cancer of the esophagus if drinking, so should advise them to drink few, and increase the inspection of cancer of the esophagus. As supplementing, a thesis in 2010 has carried on research to the situation of the continent crowd, the conclusion is similar - -The person who exists drunking of ALDH2 genetic defect is higher than the probability of suffering from cancer of the esophagus of the persons who get drunk normally.

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